CD38 and Sepsis: CLP-induced sepsis increased both the frequency (3.8 ± 1.1 % versus 0.65 ± 0.32 %, P < 0.01, Fig. 2f) and total cell count (1.5 × 105 ± 0.8 × 105/ml versus 0.3 × 105 ± 0.2 × 105/ml, P < 0.05, Fig. 2f) of the early CD34+ CD38− HSPCs.