XRCC1 and colorectal carcinoma: Our results showed that the subjects with 399Arg/Trp (OR = 1.46, 95 % CI 1.06–2.01) or 399Trp/Trp genotype (OR = 1.93, 95 % CI 1.05–3.54) had a significantly increased risk for CRC, when compared with the individuals carrying 399Arg/Arg genotype of XRCC1 gene, which was consistent with the above-mentioned findings in Egypt and Korea.