However, infection of mice homozygously deficient for p50 and heterozygous for p65 (referred to as 3X mice) with CDT-producing C. jejuni [76], promotes colonization of the gastro-intestinal tract and is associated with enhanced gastritis and hyperplasia at four months post-infection, compared to infection with an isogenic strain carrying a mutated cdtB gene, thus deficient for the genotoxic activity. The gene discussed is NFKB1; the disease is infection.