The localization of PLEKHA7, ZO-1 and E-cadherin in the glandular structures of well-differentiated ductal carcinomas was very similar to that of normal breast tissue, for example PLEKHA7 was accumulated at the apical zonular belts of the cells lining the lumen of the tubules (Fig 2B’–2B”‘, arrows). This evidence concerns the gene TJP1 and breast ductal adenocarcinoma.