Although we did not observe an association between levels of MOAP-1 expression and breast cancer family history, recurrence, death, or Her2-amplification, we did discover a significantly higher proportion of patients expressing low MOAP-1 with ER-negative and PR-negative breast tumors (Fig. 2E (Her2+ amplified and TNBC) and Table 1). Here, ESR1 is linked to breast carcinoma.