Furthermore, a clinical trial of the anti‐angiogenesis drugs bevacizumab and cediranib on advanced colorectal cancer patients established that patients with high concentrations of serum LDHA (treated with cediranib) had better overall survival (OS), whereas patients with low concentrations of serum LDHA (treated with bevacizumab) had a better OS, although these results were not significant 4. This evidence concerns the gene LDHA and colorectal cancer.