In brain tumors, a study in GBMs revealed that LDHA, secreted by the tumor, induced the transcription and expression of natural killer group 2 member D (NKG2D) ligands, ULBP‐1 (UL16 binding protein 1) and MICB [major histocompatibility complex (MHC) class I chain‐related B)], on circulating monocytes and tumor infiltrating myeloid cells 18. Here, ULBP1 is linked to brain neoplasm.