Ventricular remodeling is changes in cell structure and function, such as myocardial fibrosis, which can be caused by a series of complex molecular and cellular mechanisms, such as metabolic abnormalities of the interstitial collagen network, changes in the TGF-β molecular pathways and changes in the MMPs [13, 14]. The gene discussed is TGFB1; the disease is Myocardial fibrosis.