Hypophosphatemia in the setting of acute infectious illness such as CAP might have several etiologies, including refeeding, insulin therapy, acute respiratory alkalosis, inadequate intake, decreased phosphorus absorption (eg. anti-acids), and the use of medications (eg. methylprednisolone, epinephrine, terbutaline, and theophylline) [13–20]. The gene discussed is INS; the disease is hypophosphatemia.