(Fig 1B) In The Cancer Genome Atlas (TCGA) collection, PTPRD is most frequently mutated in cutaneous melanoma (59/344 cases, 17.2%), followed by lung adenocarcinoma (33/230 cases, 14.3%), and stomach adenocarcinoma (30/289 cases, 10.4%). The gene discussed is PTPRD; the disease is cutaneous melanoma.