TGFB1 and breast carcinoma: First, our work (Figs 1C–1E, 2, 3 and 5 and S6 Fig) and the work of others [45] have demonstrated that TGFβ induces EMT/migration/invasion/metastasis in breast cancer cells with high PEAK1 expression (i.e., MCF10CA1h and MDA-MB-231), but has little or no effect on migration/invasion in low PEAK1-expressing breast cancer cells (i.e., MCF-7 and MCF10CA1a).