BRAF and melanoma: It is also of interest that while Panc-1 and HPDE cells strongly express CD204 and CD206, they do not express pan-macrophage markers like CD68 (Gene ID#968) or CD14 (Gene ID#929): CD68 and CD14 are unlikely to contribute to altered metabolic requirements, although it is of interest that activating BRAF mutations do alter metabolic pathways in melanoma [52].