It is a functional receptor which mediates the endocytosis of low density lipoproteins, implying lipid metabolism, and its expression has also been linked with various cancers as well as with intralymphatic metastasis [44] CD206 (Gene ID#4360) is MRC1, the mannose receptor, C type 1; it is involved in glycoprotein metabolism, and curiously has also been shown to be involved with CD44 in lymphatic trafficking [45]. The gene discussed is CD44; the disease is cancer.