We previously reported that among the first three genetic loci for AF identified by GWAS in European ancestry populations, only rs2200733 at the PITX2c locus on 4q25 and rs2106261 in ZFHX3 on 16q22, but not rs13376333 in KCNN3, were replicated in the Chinese Han populations [6,9]. The gene discussed is KCNN3; the disease is atrial fibrillation.