To investigate the functions of these genes in signal transduction in tumor cells, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis was performed, and 5 differentially expressed genes were identified, including AKT3, ECM1, LPAR1 (also known as GPCR), NR4A1 (also known as NUR77), and PRKCB. The gene discussed is AKT3; the disease is neoplasm.