Using GSEA we found that silencing of RTVP-1 induced downregulation of genes that are targets of the TFs STAT3 and C/EBPβ, which further supports our data that RTVP-1 is a downstream mediator of STAT3 and C/EBPβ effects on the mesenchymal transformation of glioma cells. The gene discussed is STAT3; the disease is glioma.