However, in swine, a similar diet-induced hypercholesteremia as in our experiments[28] was associated with a markedly reduced PPAR-α and PPAR-γ expression[29], coinciding with impaired glucose tolerance[28, 29], arterial hypertension[28], increased transaminase activities[29], and aggravated oxidative stress[28]. Here, PPARA is linked to Impaired glucose tolerance.