Contrary to the findings from the present study, a postmortem study by Ridge et al. [43] showed that the expression levels of GRIN1, GRIN2A, and GRIN2B mRNAs were lowered in both superior frontal and primary motor cortex tissues of alcoholic subjects with liver cirrhosis in comparison to nonalcoholic control subjects or alcoholic subjects without comorbid disorders. Here, GRIN1 is linked to cirrhosis of liver.