TP53 and neoplasm: The correlation coefficient between both Ki67 index and p53 mutation and the size of tumor and age was calculated using Pearson correlation test, which showed that the correlations between the size of tumor and Ki67 expression (r = 0.139 and P = 0.02) and between age and Ki67 expression (r = −0.181 and P = 0.001) were significant, whereas the correlations with p53mutation were not significant (r = 0.91 and P = 0.19) (Table 6).