Here we report a unique case of MPO-ANCA microscopic polyangiitis affecting primarily the lung in a patient with a history of MPO-ANCA microscopic polyangiitis with renal-limited vasculitis and coexisting IgA deposits as well as idiopathic thrombocytopenic purpura (ITP). The gene discussed is CD79A; the disease is thrombocytopenic purpura.