The second pivotal trial (Trial Assessing Injectable Interferon versus FTY720 Oral in Relapsing-Remitting Multiple Sclerosis, TRANSFORMS) confirmed preliminary results, as fingolimod proved to be effective in reducing the ARR and MRI disease activity measures but failed to slow disability progression, compared to interferon beta 1-a [9]. Here, IFNB1 is linked to multiple sclerosis.