Therefore, significantly higher frequency of CDH23 mutations (15.4 vs 3.1 %) obtained from a different Korean cohort with nonsyndromic arSNHL not limited to prelingual SNHL cases [18] (Table 2) may suggest CDH23 mutations also significantly contribute to adult-onset postlingual arSNHL in Koreans. This evidence concerns the gene CDH23 and sensorineural hearing loss disorder.