IL17A and obesity due to melanocortin 4 receptor deficiency: On the basis of the above data and to better understand the mechanisms causing or maintaining the dysfunction of adipose tissue, the aim of the present study was to assess IL-17A in low-grade chronic inflammation due to obesity by: (1) evaluating the expression of IL-17A and several adipo/cytokines in both visceral (VAT) and subcutaneous adipose tissue (SAT); (2) analyzing the circulating levels of IL-17A and other adipo/cytokines from morbidly obese patients and normal-weight healthy subjects.