YAP1 and cancer: For studies evaluating OS, subgroup analysis by staining location demonstrated that YAP1 positive expression was significantly related with poor OS for both nuclear staining (HR: 1.474, 95% CI: 1.203–1.807, p = 0.729 without heterogeneity) and nuclear combining with cytoplasmic staining (HR: 2.237, 95% CI: 1.548–3.232, p <0.001) in patients with cancers.