In an analysis of peripheral T-cell lymphomas (PTCL), Vasmatzis and Feldman’s group identified 13 recurrent abnormalities including inter and intra chromosome rearrangements in which five of them occur within P53 related genes (TP53, TP63, CDKN2a, WWOX and ANKRD11) and precise breakpoints were successfully confirmed by PCR and Sanger sequencing. This evidence concerns the gene TP63 and mature T-cell and NK-cell non-Hodgkin lymphoma.