Evidence further suggest that the Nrf2-Keap1 system contributes to protection against various diseases, such as cancer, liver toxicity and inflammation [41], and has relevance in the physiopathology of various neurological diseases, such as Alzheimer’s disease [54], Parkinson’s disease [34], multiple sclerosis [55], amyotrophic lateral sclerosis [56], Huntington’s disease [35], and epilepsy [57]. Here, NFE2L2 is linked to nervous system disorder.