As reported, mutants in the NF1 gene lead to high-grade gliomas and MPNSTs [43], those in BRCA2, mybl2, and espl1 lead to testicular neoplasias [44, 45], those in the pen/lgl2, bmyb and cds genes cause epidermal neoplasia [32, 46, 47], and GSTT1 deletion related to lymphoma progression [48], and vhl mutants lead to an increase in hepatic and intestinal tumors [33]. The gene discussed is MYBL2; the disease is glioma.