Since the use of Ang-1 offers clinical benefits as a quiescence agent for endothelial cells in an elegant model of sepsis,76 it is conceivable that restoring the Ang-2/Ang-1 balance in favor of Ang-1 would block and potentially reverse the ongoing inflammatory processes in CM patients at the time of admission (Figure 3B). Here, ANGPT1 is linked to Sepsis.