KLK3 and acute myeloid leukemia: Objective responses occurred partly very fast (<= 8 weeks) in very rapidly progressive chemoresistant diseases, such as in CRPC (n = 10, PSA decline >50 %), AML (n = 5), cHL (n = 3), mLCH (n = 2), or in contrast, very delayed in RCCC II, after 4 to 6 months (10 of 15 responders, thereof n = 2 pathologic CRs).