Further, transcripts implicated in steroidogenesis, cholesterol biosynthesis, transport and metabolism (AUP1[105], FDFT1[106], PAWR[107], SLCO2B1[108], VAMP4[109]), progesterone synthesis (BLVRB[110], BMP4[90]) and linked to obesity-related reduced fertility (FANCC[111], PPT1[112], SFRP4[102]) exhibited significant changes in expression (p<0.05, FDR<0.15). The gene discussed is FDFT1; the disease is obesity due to melanocortin 4 receptor deficiency.