To determine whether the effect of miR-373 on cancer migration is mediated mainly through ITGA2, miR-373 precursor was co-transfected into MCF-7 cells, together with a vector expressing ITGA2 lacking its 3’UTR (ITGA2), or a vector expressing ITGA2 containing its 3’UTR (ITGA2-3’UTR). The gene discussed is ITGA2; the disease is cancer.