Methylation of one of these regulatory sites, OXTR CpG site -934, has been implicated in autism spectrum disorder (Gregory et al., 2009), callous-unemotional traits (Dadds et al., 2013), and individual variability in social perception (Jack et al., 2012; Puglia et al., 2015) pointing to an important role for the actions of DNA methylation on OXTR in behavior. The gene discussed is OXTR; the disease is autism spectrum disorder.