A similar study by To et al. showed significantly higher levels of granulocyte colony-stimulating factor (G-CSF), IFNα2, IL1α, IL6, IL8, IL10, IL15, IP10, and MCP1 in plasma samples of patients that developed ARDS and died than in those patients that developed mild disease at early times after onset of symptoms (48). This evidence concerns the gene CXCL10 and acute respiratory distress syndrome.