For this purpose we utilized the micro-satellite-instability, p53, BRAF and PTEN wild-type HCT-116 and LoVo colon cancer cell lines plus the p53 mutated micro-satellite-stable, BRAF mutated, PTEN wild type HT-29 cell line (Ahmed et al., 2013). The gene discussed is BRAF; the disease is colonic neoplasm.