HCLS1 and colorectal cancer: The presence of the colorectal cancer pathway is explained by the non-specific inflammatory genes involved such as ACVR1C, AKT2, FZD6, MSH2, and TGFBR1. For the CSP study a number of upregulated genes corresponded to the Adipocytes module, which features many immune related genes including CD53, HCLS1 and IFI30.