Interferon-induced transmembrane protein 3 (IFITM3) is involved in innate responses to flu, dengue fever, and West Nile virus (Brass et al., 2009), and it has recently been shown that S-palmitoylation of IFITM3 controls clustering in membrane compartments and its antiviral activity (Yount et al., 2010). The gene discussed is IFITM3; the disease is dengue disease.