Similarly, the levels of BM plasma IL-22 in ND, CR MM patients and controls were not significantly different (ND: median, 59.72, range: 49.00-67.18 pg/ml, P>0.05; CR: median, 56.47, range: 53.56-67.82 pg/ml, P>0.05; control: median, 61.02, range: 53.56-62.64 pg/ml) (Fig. 3F). This evidence concerns the gene IL22 and Miyoshi myopathy.