Considering the role of TLR molecules in the development of T. gondii infection, as well as TLR genetic changes in pregnancy disorders, we decided to describe in this report the prevalence rates of the genotypes and alleles at the TLR4 896 A>G, 1196 C>T, and TLR9 1635 G>A SNPs in fetuses and newborns congenitally infected with T. gondii and compare them to the prevalence rates observed in uninfected controls. The gene discussed is TLR4; the disease is pregnancy disorder.