Taking into account all the analyzed SNPs, the multiple ACG variant at the TLR4 896 A>G, 1196 C>T, and TLR9 1635 G>A polymorphic sites was most common among the fetuses and newborns with congenital toxoplasmosis, with a prevalence rate of 52.8 %. This evidence concerns the gene TLR4 and congenital toxoplasmosis.