GADD45G and Familial prostate cancer: For example, asm¦33039309, which has a significant H3K27ac mark at its genomic locus in the LNCap prostate cancer cell line (Fig5C), was more frequently expressed in prostate cancer than in normal samples (54% vs. 31%; Fig5D), with increased expression of its adjacent gene, GADD45G, in normal or cancer samples that express this transcript (Fig5E).