CCR4 and infection: Besides, genes associated with innate molecular immunity were also up-regulated in the intestine tissue at 4 hour post infection with E. granulosus, which encode Th1 cytokines (IL2, IL3, TNF13 B) and related chemokines(CXCL2, CXCL5, CXCL9, CXCL17, CCL28), as well as Th2 cytokiens and related chemokines (IL13, CCR3, CCR4).