The abnormality of coagulation factors in cirrhosis patients aggravates the disease, resulting in poor coagulation status and bleeding tendency.8,19 The coagulation time of cirrhosis patients is obviously prolonged: PT, APTT, thrombin time (TT), and fibrin (Fib) levels all change to some extent, with PT, TT, and APTT being significantly prolonged and Fib being significantly decreased.9,20 Along with the deterioration of cirrhosis, liver function and coagulation function can progressively worse. Here, FBL is linked to Cirrhosis.