There were 2 patients with UCTD, including a single patient who interestingly presented with some features seen in scleroderma (ie, Raynaud's, puffy hands, dilated nailfold capillaries, and anti-Pm1-Scl antibodies) albeit not satisfying diagnostic criteria for scleroderma.57 There was a single patient with psoriatic arthritis treated with TNF-inhibitor therapy. The gene discussed is TMEM11; the disease is scleroderma.