Recently, Huang et al. suggested that embelin inhibits epithelial-to-mesenchymal transition (EMT) by upregulating E-cadherin and inhibiting the expression of EMT-inducing transcription factors [38], including Snail, Slug, and ZEB1, and that this is correlated with MMPs inactivation in pancreatic cancer cells. This evidence concerns the gene CDH1 and familial pancreatic carcinoma.