While there was no significant difference in plasma TF antigen levels between AML patients (n = 63) and healthy controls (n = 10), DIC patients (n = 8) had significantly higher levels than non-DIC patients (n = 55) and controls (Fig. 4c), further indicating that TF expression is upregulated in AML-associated DIC. Here, TF is linked to acute myeloid leukemia.