CCAR2 and cancer: Moreover, it has been reported that the expression of DBC1 is associated with poor prognosis of various human malignant tumors, including gastric carcinoma13, esophageal carcinomas17, breast carcinomas12, 16, colorectal carcinomas8, clear cell renal cell carcinomas10, diffuse large B cell lymphomas9, ovarian carcinomas14, and soft-tissue sarcomas11.