Overall, even if a tendency for an increased basal activity of myosin could be observed for both AGE, these experiments (Fig 4A and 4B) indicated there were no significant differences among PBS (73.7±5.9%), AGE-HSA (95.8±3.4%) and CML-HSA (83.1±8.4%). The gene discussed is MYH14; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.