We performed multivariate analysis to identify clinicopathological factors that had an important impact on the metastasis of #11 among pN2 patients, but no significant difference was observed in any variables such as age (>70, p = 0.41), smoking habits (BI > 400, p = 0.26), tumor marker [Carcinoembryonic antigen (CEA)>5, p = 0.72], tumor size (>30 mm, p = 0.11), pathology [adenocarcinoma (AD) or non-AD, p = 0.72], and differentiation index (poorly or not, p = 0.91). The gene discussed is CEACAM5; the disease is adenocarcinoma.