IL2 and cancer: In addition, MSC-based gene therapy for various solid tumors improves host anticancer responses through releasing the foreign gene-encoded proteins, such as iNOS, IL-2 and IL-12.138, 139, 140 Optimistically, some clinical trials for evaluating the specific potentials of MSCs on treating cancer and cancer regimen-related disorders are being carried out (ClinicalTrials.gov data).