Thus, we analyzed any correlations between PELP1, HER1 and NRG1. We observed PELP1 to be negatively correlated with both HER1 (Fig 3; r = -0.343, P = 0.033) and NRG1 (r = -0.367, P = 0.022) within tumor tissue. This evidence concerns the gene NRG1 and neoplasm.