SLC18A2 and Parkinson disease: It is not surprising, then, that two single-nucleotide polymorphisms (SNPs) in the promoter region of the VMAT2 gene, rs363371 and rs363324, have been associated with risk of PD in an Italian population: the A allele of rs363371 and the G allele of rs363324 were reported to decrease the risk of developing PD [15].