In 2010, the Joint Task Force on Practice Parameters, representing the AAAAI; the American College of Allergy, Asthma and Immunology (ACAAI); and the Joint Council of Allergy, Asthma and Immunology, the term anaphylaxis was continued to be used for IgE-mediated reactions for the purpose of the Practice Parameter document, while non-IgE-mediated reactions producing the same clinical response were referred to as anaphylactoid although it was acknowledged that the World Allergy Organization (WAO) had suggested that the term ‘anaphylactoid reaction' be eliminated.7 The gene discussed is IGHE; the disease is asthma.