IL1R2 and asthma: In this study, we detected higher levels of DNA-Me at IL1R2 among affected individuals (i.e., with asthma, atopy, or both) as compared to non-affected controls (Δβ = 8.02 %, p value = 0.013, and Δβ = 3.72 %, p value = 0.012 for IL1R2-CpG2 and the mean for CpG3 and CpG4, respectively (Table 2, Fig. 1b)).